In 2012, Macmanus was named permanent representative to the UN mission in Vienna and to the International Atomic Energy Agency. There, he participated in negotiations for the Iran nuclear deal. During a 2013 negotiating session, Iran accused Israel of genocide. Macmanus, along with representatives of Canada and Australia, stormed out of the session in protest. But after the agreement was finalized, Secretary of State John Kerry named Macmanus to coordinate implementation of the deal with Iran.
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